Uniquely placed to optimise the properties of Microbial Natural Products
Isomerase Therapeutics is a microbial natural product discovery and development services company based in Cambridge, UK. Isomerase has particular expertise in optimised microbial natural products and uses cutting edge biosynthetic engineering, synthetic biology and semi-synthetic chemistry to support its partners research and development efforts.
Since its formation in 2012, Isomerase has become an established and successful Natural Products Discovery and Development Service Provider with a base of clients and successful projects. We moved into our first laboratory in 2013 at the Science Village on Chesterford Research Park and have expanded our presence there over the last six years to a company of around 30 employees.
Highlights have included winning the Queen’s Award for International Trade in 2017.
We have expanded our capabilities so we cover almost all aspects of discovery and development of Natural Products, such as genetic manipulation and strain improvement of microorganisms, genome sequence analysis, protein and peptide expression and isolation, small scale fermentation and process development, DSP, compound isolation and analytical development and synthetic chemistry. In addition, we can manage all other aspects required for a commercially successful program on behalf of the partner if required, such as scaled manufacture and tailored drug discovery screening cascades.
We offer bespoke biosynthetic engineering, synthetic biology technologies and semi-synthetic chemistry support, along with extensive drug discovery and development expertise on a FTE basis to partners looking for more than just a CRO. Isomerase Therapeutics can help you take your chosen product from an interesting hit or concept to a high value commercial product.